Description

1-Ethoxy-2-Fluoro-3-Methoxy-4-Nitrobenzene is a high-purity, multi-functional aromatic building block characterized by its unique substitution pattern. This compound is critical for advanced organic synthesis, particularly in the development of complex molecules for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries who require precise and reliable intermediates for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, leveraging its nitro and fluoro substituents for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating specialized aromatic cores used in electronic display technologies.
• Dye & Pigment Synthesis: Employed in the production of high-performance, light-fast dyes and organic pigments.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into polymer chains.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	1-Ethoxy-2-Fluoro-3-Methoxy-4-Nitrobenzene
CAS No.	1072945-58-4
Molecular Formula	C9H10FNO4
Molecular Weight	215.18 g/mol
Synonyms	2-Fluoro-3-methoxy-4-nitroanisole; 4-Nitro-2-fluoro-1,3-dimethoxybenzene (isomer); 1-Ethoxy-2-fluoro-3-methoxy-4-nitrobenzene; 2-Fluoro-1,3-dimethoxy-4-nitrobenzene (related isomer); Benzene, 1-ethoxy-2-fluoro-3-methoxy-4-nitro-; Ethyl 2-fluoro-3-methoxy-4-nitrobenzene ether; 4-Nitro-2-fluoro-1,3-diethoxybenzene (variant); 1072945-58-4
EINECS	Contact for details

Quality Control

Our 1-Ethoxy-2-Fluoro-3-Methoxy-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.