Description

5-Fluoro-L-Tryptophan Hydrochloride is a fluorinated derivative of the essential amino acid L-tryptophan, supplied as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical building block in pharmaceutical research and development, particularly for the synthesis of novel bioactive molecules and peptide-based therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, proteomics, and the development of targeted therapies.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of fluorinated peptides and novel drug candidates targeting neurological and oncological pathways.
• Biochemical Research: Used in metabolic pathway studies, enzyme-substrate interaction assays, and as a tool compound to investigate tryptophan metabolism and fluorinated amino acid incorporation.
• Proteomics & Peptide Synthesis: Incorporated into custom peptides to modulate their biological activity, stability, and binding properties for research and diagnostic applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, MS).
• Labeled Compound Synthesis: Acts as a starting material for the preparation of isotopically labeled (e.g., 13C, 15N) fluorotryptophan derivatives for advanced research.

Basic Information

Product Name	5-Fluoro-L-Tryptophan Hydrochloride
CAS No.	1065638-25-6
Molecular Formula	C₁₁H₁₂FN₂O₂·HCl
Molecular Weight	256.68 g/mol
Synonyms	(S)-2-Amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid hydrochloride; 5-F-DL-Tryptophan HCl; 5-Fluoro-DL-tryptophan monohydrochloride; 5-Fluorotryptophan hydrochloride; F5W-OH·HCl; 5-FTrp·HCl
EINECS	Contact for details

Quality Control

Our 5-Fluoro-L-Tryptophan Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets rigorous research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.