Description

6-Fluoro-8-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block characterized by its unique fluorine-substituted quinoline core. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly for kinase inhibitors, antiviral agents, and anti-cancer therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and trifluoromethyl groups contribute to efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other fluorinated functional materials.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies due to its distinct spectroscopic signature.
• Catalyst & Ligand Development: Utilized in the design of novel metal-organic complexes and catalysts for specialized organic transformations.

Basic Information

Product Name	6-Fluoro-8-(Trifluoromethyl)Quinoline
CAS No.	1065074-24-9
Molecular Formula	C10H5F4N
Molecular Weight	215.15 g/mol
Synonyms	8-(Trifluoromethyl)-6-fluoroquinoline; 6-Fluoro-8-trifluoromethylquinoline; Quinoline, 6-fluoro-8-(trifluoromethyl)-; 1065074-24-9
EINECS	Contact for details

Quality Control

Our 6-Fluoro-8-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.