Description

Mizolastine (Dihydrochloride) is a high-purity, small molecule pharmaceutical intermediate and active ingredient. This compound is critical for research and development in the pharmaceutical industry, particularly for its role as a potent and selective histamine H1-receptor antagonist. It is primarily sought after by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers engaged in the development of novel antihistamine therapeutics. Our supply ensures consistent quality and reliable availability for global production and research needs.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of antihistamine medications.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies of histamine receptor pathways.
• Preclinical Development: Serves as a key intermediate in the synthesis and optimization of new therapeutic candidates targeting allergic conditions.
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories.
• Fine Chemical Synthesis: Employed as a building block for the preparation of more complex molecules in medicinal chemistry.

Basic Information

Product Name	Mizolastine (Dihydrochloride)
CAS No.	1056596-82-7
Molecular Formula	C24H25FN6O · 2HCl
Molecular Weight	505.42 g/mol
Synonyms	Mizolastine Dihydrochloride; Mizolastine HCl; SL 85.0324-10; 2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone dihydrochloride; 4(3H)-Pyrimidinone, 2-[[1-[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our Mizolastine (Dihydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.