Description

(6β,11β)-21-(Acetyloxy)-11,17-Dihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione CAS NO 1048031-82-8 is a high-purity synthetic steroid derivative, specifically a modified pregnadiene, designed for advanced pharmaceutical research and development. This compound is of significant value as a key intermediate or reference standard in the synthesis and study of novel corticosteroid analogs with potential therapeutic applications. It is primarily required by R&D laboratories, pharmaceutical manufacturers, and academic institutions engaged in endocrinology, anti-inflammatory drug discovery, and metabolic research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel corticosteroid and glucocorticoid receptor-targeting drug candidates.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related steroid compounds.
• Biochemical Research: Employed in in vitro studies to investigate steroid hormone receptor binding affinity, metabolic pathways, and structure-activity relationships (SAR).
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis, medicinal chemistry, and steroid biochemistry.
• Process Development: Acts as a benchmark compound for scaling up and optimizing synthetic routes within process chemistry and chemical development units.

Basic Information

Product Name	(6β,11β)-21-(Acetyloxy)-11,17-Dihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione
CAS No.	1048031-82-8
Molecular Formula	C24H32O6
Molecular Weight	416.51 g/mol
Synonyms	6β,11β,17,21-Tetrahydroxy-6-methylpregna-1,4-diene-3,20-dione 21-acetate; 11β,17-Dihydroxy-6-methyl-21-(acetyloxy)pregna-1,4-diene-3,20-dione; 6β-Methylprednisolone 21-acetate (related analog); 21-Acetoxy-11β,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione; (6β,11β)-Pregnadiene derivative; 6-Methylprednisolone 21-acetate isomer; Steroid intermediate 1048031-82-8.
EINECS	Contact for details

Quality Control

Our (6β,11β)-21-(Acetyloxy)-11,17-Dihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.