Description

2-Fluoro-5-Methyl-Dl-Phenylalanine is a fluorinated derivative of the amino acid phenylalanine, serving as a critical non-natural amino acid building block. This compound matters for its role in modulating the biological activity, metabolic stability, and physicochemical properties of peptides and small molecule pharmaceuticals. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for drug discovery, peptide synthesis, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for oncology and CNS-targeted therapies.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate fluorine atoms, enhancing peptide stability and bioavailability.
• Proteomics & Biochemistry Research: Acts as a tool compound for studying enzyme-substrate interactions, metabolic pathways, and protein engineering.
• Agrochemical Development: Serves as a building block for designing new herbicides, pesticides, and plant growth regulators with improved efficacy.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for imaging and diagnostic applications.
• Material Science: Potential precursor for specialty polymers and advanced materials with unique electronic or surface properties.

Basic Information

Product Name	2-Fluoro-5-Methyl-Dl-Phenylalanine
CAS No.	1043500-50-0
Molecular Formula	C10H12FNO2
Molecular Weight	197.21 g/mol
Synonyms	DL-2-Fluoro-5-methylphenylalanine; (RS)-2-Amino-3-(2-fluoro-5-methylphenyl)propanoic acid; 5-Methyl-2-fluorophenylalanine; 2-Fluoro-5-methyl-DL-α-phenylalanine; 2-Fluoro-5-methyl-DL-α-aminohydrocinnamic acid; (±)-2-Fluoro-5-methylphenylalanine; Fmoc-2-Fluoro-5-methyl-DL-Phenylalanine (precursor); 2-Fluoro-5-methyl-homophenylalanine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request. We adhere to a quality management system to support research and cGMP-grade manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.