Description

4-(3-Fluorophenyl)Oxane-4-Carbonitrile is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a fluorinated aromatic ring with a tetrahydropyran (oxane) scaffold bearing a nitrile functional group, enabling diverse chemical transformations. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and complex molecular libraries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine atom.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of advanced polymers and liquid crystals, where the fluorophenyl and oxane units contribute to specific thermal and optical properties.
• Chemical Biology Probe Synthesis: Utilized to build molecular tools for studying enzyme function and biological pathways.

Basic Information

Product Name	4-(3-Fluorophenyl)Oxane-4-Carbonitrile
CAS No.	1035261-79-0
Molecular Formula	C12H12FNO
Molecular Weight	205.23 g/mol
Synonyms	4-(3-Fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile; 4-(3-Fluorophenyl)tetrahydropyran-4-carbonitrile; 4-Cyano-4-(3-fluorophenyl)tetrahydropyran; 4-(3-Fluorophenyl)-4-cyanotetrahydropyran; 4-(3-Fluorophenyl)-4-cyanotetrahydro-2H-pyran; 4-(m-Fluorophenyl)tetrahydro-2H-pyran-4-carbonitrile; 1035261-79-0
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Fluorophenyl)Oxane-4-Carbonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process development. A detailed Certificate of Analysis (COA), including results from HPLC, GC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.