Description

Endoxifen Hcl is a high-purity, non-steroidal selective estrogen receptor modulator (SERM) and the primary active metabolite of tamoxifen. This compound is critical for advanced pharmaceutical research and development, offering a direct and potent mechanism of action. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in oncology research, drug discovery, and the development of novel therapeutic agents targeting estrogen receptor-positive conditions.

Application

• Pharmaceutical Intermediate: Serves as a key active pharmaceutical ingredient (API) in the development and manufacturing of advanced breast cancer therapeutics.
• Biomedical Research: Used as a reference standard and investigational compound in preclinical and clinical studies focused on estrogen receptor biology and cancer mechanisms.
• Drug Discovery: A vital tool for screening and developing new SERMs and combination therapies for hormone-dependent cancers.
• Metabolite Studies: Employed in pharmacokinetic and pharmacodynamic research to understand tamoxifen metabolism and efficacy.
• Academic Research: Utilized in university and institutional labs for fundamental studies in endocrinology and oncology.

Basic Information

Product Name	Endoxifen Hcl
CAS No.	1032008-74-4
Molecular Formula	C26H30ClNO2 • HCl
Molecular Weight	464.44 g/mol
Synonyms	Endoxifen Hydrochloride; (Z)-Endoxifen; (Z)-4-Hydroxy-N-desmethyltamoxifen Hydrochloride; N-Desmethyl-4-hydroxytamoxifen Hydrochloride; Z-Endoxifen HCl; Norendoxifen Hydrochloride; FC-1271a
EINECS	Contact for details

Quality Control

Our Endoxifen Hcl is manufactured under strict quality management systems to ensure the highest standards of purity and consistency, suitable for research and development applications. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity verification. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.