Description

1-Bromo-2-Chloro-5-Fluoro-4-Nitrobenzene is a high-purity, multi-substituted aromatic building block of significant importance in advanced organic synthesis. Its unique halogen and nitro substitution pattern makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aromatic rings.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the specific halogen pattern influences biological activity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functional complexity.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized halogenated dyes and colorants.

Basic Information

Product Name	1-Bromo-2-Chloro-5-Fluoro-4-Nitrobenzene
CAS No.	1027833-17-5
Molecular Formula	C6H2BrClFNO2
Molecular Weight	254.44 g/mol
Synonyms	2-Bromo-1-Chloro-4-Fluoro-5-Nitrobenzene; 4-Bromo-3-Chloro-6-Fluoronitrobenzene; Benzene, 1-bromo-2-chloro-5-fluoro-4-nitro-; 5-Fluoro-4-nitro-1-bromo-2-chlorobenzene; 2-Chloro-5-fluoro-4-nitro-1-bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-5-Fluoro-4-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.