Description

2-Bromo-6-Fluoro-4-Methylbenzonitrile is a high-purity, multi-functional halogenated aromatic nitrile building block. This compound is valued for its unique molecular architecture, which facilitates the synthesis of complex molecules in advanced research and development. It is primarily utilized by pharmaceutical, agrochemical, and advanced material scientists as a key intermediate for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for enhanced bioactivity.
• Liquid Crystal & OLED Material Research: Used in the development of advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromatic core and polar nitrile group.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.
• Functional Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where halogen and nitrile groups modify color properties and stability.
• Chemical Biology & Proteomics: Utilized as a molecular probe or a tagging reagent in chemical biology research for studying protein interactions and functions.

Basic Information

Product Name	2-Bromo-6-Fluoro-4-Methylbenzonitrile
CAS No.	1023971-89-2
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	2-Bromo-6-fluoro-4-methylbenzonitrile; 4-Methyl-2-bromo-6-fluorobenzonitrile; 6-Fluoro-2-bromo-p-tolunitrile; Benzonitrile, 2-bromo-6-fluoro-4-methyl-; 2-Bromo-6-fluoro-4-methyl-benzonitrile; 1023971-89-2
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-Fluoro-4-Methylbenzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.