Description

2-(4-Fluorophenoxy)Benzonitrile CAS NO 1020922-27-3 is a high-purity aromatic nitrile derivative featuring a fluorophenoxy substituent, serving as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block. Its unique molecular structure makes it essential for constructing complex molecules in medicinal chemistry and agrochemical research. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the fluorophenoxy moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Intermediate for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Used to develop molecular probes and tags for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	2-(4-Fluorophenoxy)Benzonitrile
CAS No.	1020922-27-3
Molecular Formula	C13H8FNO
Molecular Weight	213.21 g/mol
Synonyms	2-(4-Fluorophenoxy)benzonitrile; Benzonitrile, 2-(4-fluorophenoxy)-; 4-Fluoro-2-phenoxybenzonitrile; 2-(p-Fluorophenoxy)benzonitrile; (4-Fluorophenoxy)benzonitrile; 1020922-27-3; 2-(4-Fluorophenoxy)phenyl cyanide
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenoxy)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.