Description

2-Fluoro-3-Nitrobenzyl Chloride is a versatile and reactive halogenated aromatic building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research, where it serves as a key precursor for introducing functionalized benzyl groups. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing fluorinated and nitro-substituted aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive benzyl chloride moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as an electrophile in various palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Derivatization Agent: Used to introduce a chromophore or a reactive handle onto other molecules for analytical or synthetic purposes.

Basic Information

Product Name	2-Fluoro-3-Nitrobenzyl Chloride
CAS No.	1020718-00-6
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	1-(Chloromethyl)-2-fluoro-3-nitrobenzene; (2-Fluoro-3-nitrophenyl)methyl chloride; α-Chloro-2-fluoro-3-nitrotoluene; 2-Fluoro-3-nitrobenzylchloride; 2-Fluoro-3-nitrobenzyl chloride; 3-Nitro-2-fluorobenzyl chloride; Benzene, 1-(chloromethyl)-2-fluoro-3-nitro-
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Nitrobenzyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.