Description

2-Ethoxy-3,5-Difluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an ethoxy group and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating fluorinated heterocycles and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoroethoxy moiety can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine atoms into polymer backbones, improving chemical resistance and thermal stability.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig aminations to build complex biaryl systems.

Basic Information

Product Name	2-Ethoxy-3,5-Difluorobenzonitrile
CAS No.	1017779-80-4
Molecular Formula	C9H7F2NO
Molecular Weight	183.16 g/mol
Synonyms	3,5-Difluoro-2-ethoxybenzonitrile; Benzonitrile, 3,5-difluoro-2-ethoxy-; 2-Ethoxy-3,5-difluorobenzene carbonitrile; 3,5-Difluoro-2-ethoxybenzonitrile; 1017779-80-4
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-3,5-Difluorobenzonitrile is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets typical research and industrial synthesis requirements, with comprehensive Certificates of Analysis (COA) provided for each shipment. We adhere to relevant industry standards and can support development projects requiring specific impurity profiles or custom specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.