Description

3-[(2,2,2-Trifluoroethoxy)Methyl]Benzonitrile is a high-value, fluorinated aromatic nitrile building block essential for advanced organic synthesis. Its molecular structure, featuring a trifluoroethoxymethyl side chain, provides unique electronic and steric properties that are critical for developing novel active compounds. This intermediate is primarily sought by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the design and production of next-generation herbicides, fungicides, and insecticides, where the fluorine moiety improves biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Modification: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or surface properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial research to explore new fluorination methodologies and catalytic reactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up services for specialized chemical entities.

Basic Information

Product Name	3-[(2,2,2-Trifluoroethoxy)Methyl]Benzonitrile
CAS No.	1016842-93-5
Molecular Formula	C10H8F3NO
Molecular Weight	215.17 g/mol
Synonyms	3-((2,2,2-Trifluoroethoxy)methyl)benzonitrile; m-((2,2,2-Trifluoroethoxy)methyl)benzonitrile; 3-(Trifluoroethoxymethyl)benzonitrile; Benzonitrile, 3-[(2,2,2-trifluoroethoxy)methyl]-; 1016842-93-5; 3-Trifluoroethoxymethyl-benzonitrile
EINECS	Contact for details

Quality Control

Our production of 3-[(2,2,2-Trifluoroethoxy)Methyl]Benzonitrile adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.