Description

3-(Aminomethyl)-4-Fluorobenzonitrile is a high-value fluorinated aromatic nitrile building block featuring both an aminomethyl and a cyano functional group. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, particularly in the development of enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands and chelating agents used in catalysis and material science.
• Fluorinated Dye & Pigment Chemistry: Employed in the research and development of advanced fluorinated colorants and functional dyes.
• Polymer Modification: Acts as a monomer or cross-linking agent for introducing fluorinated and reactive cyano/amino groups into polymer backbones.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	3-(Aminomethyl)-4-Fluorobenzonitrile
CAS No.	1016798-28-9
Molecular Formula	C8H7FN2
Molecular Weight	150.16 g/mol
Synonyms	4-Fluoro-3-(aminomethyl)benzonitrile; 3-(Aminomethyl)-4-fluorobenzonitrile; 4-Fluoro-3-(aminomethyl)benzonitrile; Benzonitrile, 4-fluoro-3-(aminomethyl)-; 3-Cyano-4-fluorobenzylamine; 4-Fluoro-3-cyanobenzylamine; (4-Fluoro-3-cyanophenyl)methanamine
EINECS	Contact for details

Quality Control

Our 3-(Aminomethyl)-4-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged use to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.