Description

2,3-Difluoro-5-Methylbenzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique substitution pattern, which introduces steric and electronic effects critical for fine-tuning the properties of advanced materials and active pharmaceutical ingredients. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging the difluoro-methylbenzonitrile scaffold.
• Liquid Crystal & OLED Materials: Serves as a precursor for constructing polarizable aromatic cores in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with enhanced thermal and chemical resistance.
• Chemical Research: Employed in academic and industrial laboratories for methodology development, such as cross-coupling reactions and cyano-group transformations.
• Coordination Chemistry: Functions as a ligand precursor for metal-organic frameworks (MOFs) and catalysts due to the nitrile group's coordinating ability.

Basic Information

Product Name	2,3-Difluoro-5-Methylbenzonitrile
CAS No.	1003712-18-2
Molecular Formula	C8H5F2N
Molecular Weight	153.13 g/mol
Synonyms	5-Methyl-2,3-difluorobenzonitrile; 2,3-Difluoro-5-methylbenzenecarbonitrile; 2,3-Difluoro-5-tolunitrile; Benzonitrile, 2,3-difluoro-5-methyl-; 1003712-18-2; 2,3-Difluoro-5-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2,3-Difluoro-5-Methylbenzonitrile is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.