Description

2,5-Difluoro-4-Methylbenzonitrile is a high-purity fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its value lies in its unique substitution pattern, which enables precise molecular modifications critical for developing new active compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and stability.
• Liquid Crystal Material Precursor: Serves as a starting material in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diode (OLED) Materials: Employed in the synthesis of electron-transport or host materials for OLED devices.
• Advanced Polymer Modification: Acts as a monomer or modifier to introduce fluorine and nitrile functionalities into specialty polymers, improving their chemical and thermal resistance.
• Chemical Research & Development: A versatile scaffold in medicinal and synthetic chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Details
Product Name	2,5-Difluoro-4-Methylbenzonitrile
CAS No.	1003708-66-4
Molecular Formula	C8H5F2N
Molecular Weight	153.13 g/mol
Synonyms	4-Methyl-2,5-difluorobenzonitrile; 2,5-Difluoro-4-methylbenzonitrile; 2,5-Difluoro-p-tolunitrile; 4-Cyano-2,5-difluorotoluene; Benzonitrile, 2,5-difluoro-4-methyl-; 1003708-66-4; 2,5-Difluoro-4-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-4-Methylbenzonitrile is produced and tested under strict quality management protocols to ensure consistency and high purity suitable for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.