Description

3-Methoxy -2,4,5-Trifluoromethylbenzonitrile is a high-value fluorinated aromatic nitrile derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its molecular architecture, featuring a methoxy group and multiple trifluoromethyl substituents, provides unique electronic and steric properties essential for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its fluorinated aromatic core.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, cyanation processes, and as a scaffold for creating complex heterocyclic compounds in academic and industrial R&D.
• Fluorine Chemistry Studies: An important compound for investigating structure-activity relationships (SAR) and the influence of polyfluorinated arenes on molecular properties.

Basic Information

Product Name	3-Methoxy -2,4,5-Trifluoromethylbenzonitrile
CAS No.	1003708-50-6
Molecular Formula	C10H6F3NO
Molecular Weight	219.16 g/mol
Synonyms	2,4,5-Trifluoro-3-methoxybenzonitrile; 3-Methoxy-2,4,5-trifluorobenzonitrile; Benzonitrile, 2,4,5-trifluoro-3-methoxy-; 2,4,5-Trifluoro-3-methoxybenzonitrile; 3-Methoxy-2,4,5-trifluorophenyl cyanide
EINECS	Contact for details

Quality Control

Our production of 3-Methoxy -2,4,5-Trifluoromethylbenzonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques, including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.