Description

3-Fluoro-5-Formylbenzonitrile is a versatile aromatic building block featuring both a formyl and a nitrile functional group on a fluorinated benzene ring. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is particularly valuable for pharmaceutical chemists and agrochemical researchers seeking to introduce specific fluorinated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Building block for organic electronic materials, such as fluorinated polymers and liquid crystals, where its structure influences electronic properties.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for bespoke synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	3-Fluoro-5-Formylbenzonitrile
CAS No.	1003708-42-6
Molecular Formula	C8H4FNO
Molecular Weight	149.12 g/mol
Synonyms	5-Cyano-3-fluorobenzaldehyde; 3-Fluoro-5-cyanobenzaldehyde; 3-Fluor-5-formylbenzonitril; 3-Fluoro-5-formylbenzonitrile; Benzaldehyde, 5-cyano-3-fluoro-; 3-Fluoro-5-aldehydrobenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Formylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.