Description

2,3-Difluoro-4-Bromonitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique combination of fluorine, bromine, and nitro substituents makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to introduce key functional groups and modulate the biological activity of target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance metabolic stability and bioavailability.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions, leveraging the reactive bromine atom.
• Nucleophilic Aromatic Substitution: The activated nitro and fluorine groups make it an excellent candidate for nucleophilic substitution reactions to create diverse aniline derivatives.
• Dye and Pigment Intermediate: Used in the research and production of specialized dyes and pigments.

Basic Information

Product Name	2,3-Difluoro-4-Bromonitrobenzene
CAS No.	1003708-24-4
Molecular Formula	C6H2BrF2NO2
Molecular Weight	237.99 g/mol
Synonyms	4-Bromo-2,3-difluoronitrobenzene; 1-Bromo-2,3-difluoro-4-nitrobenzene; Benzene, 1-bromo-2,3-difluoro-4-nitro-; 2,3-Difluoro-4-nitro-1-bromobenzene; 2,3-Difluoro-4-nitro-bromobenzene; 4-Nitro-2,3-difluorobromobenzene
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Bromonitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.