Description

2-Amino-5-Bromo-6-Fluoro-3-Iodobenzonitrile is a highly functionalized, multi-halogenated benzonitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and iodine substituents on an aromatic ring, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective applications.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the halogen atoms contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: The amino and nitrile groups provide handles for creating novel chelating ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	2-Amino-5-Bromo-6-Fluoro-3-Iodobenzonitrile
CAS No.	1000577-88-7
Molecular Formula	C7H3BrFIN2
Molecular Weight	355.92 g/mol
Synonyms	5-Bromo-6-fluoro-2-amino-3-iodobenzonitrile; 3-Iodo-2-amino-5-bromo-6-fluorobenzonitrile; 2-Amino-3-iodo-5-bromo-6-fluorobenzonitrile; Benzonitrile, 2-amino-5-bromo-6-fluoro-3-iodo-; 1000577-88-7; 5-Bromo-6-fluoro-3-iodoanthranilonitrile; 2-Cyano-4-bromo-5-fluoro-6-iodoaniline
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Bromo-6-Fluoro-3-Iodobenzonitrile is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.