Description

Benzeneacetonitrile, 2-(Difluoromethyl)- is a specialized fluorinated organic building block, identified by CAS NO 1000556-48-8. This compound is valued for its unique difluoromethyl-substituted aromatic nitrile structure, which is critical for introducing fluorine atoms into complex molecules to modulate their physicochemical and biological properties. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating the metabolically stable difluoromethyl group.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for fluorinated polymers, liquid crystals, and other specialty materials with tailored properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Benzeneacetonitrile, 2-(Difluoromethyl)-
CAS No.	1000556-48-8
Molecular Formula	C9H7F2N
Molecular Weight	167.16 g/mol
Synonyms	2-(Difluoromethyl)benzeneacetonitrile; 2-(Difluoromethyl)phenylacetonitrile; (2-(Difluoromethyl)phenyl)acetonitrile; α-(2-(Difluoromethyl)phenyl)acetonitrile; 2-(2-Difluoromethylphenyl)acetonitrile; Benzeneacetonitrile, α-(difluoromethyl)-; Difluoromethylphenylacetonitrile
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, 2-(Difluoromethyl)- is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.