Description

2-Methoxy-5-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. Its molecular structure, featuring both a methoxy and a trifluoromethyl group, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Organic Electronics: Employed in the synthesis of electron-deficient aromatic units for organic semiconductors and OLED materials.
• Chemical Research: A valuable building block in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development and scale-up projects.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Phenylacetonitrile
CAS No.	1000542-90-4
Molecular Formula	C10H8F3NO
Molecular Weight	215.17 g/mol
Synonyms	[2-Methoxy-5-(trifluoromethyl)phenyl]acetonitrile; (2-Methoxy-5-(trifluoromethyl)phenyl)acetonitrile; 2-Methoxy-α-(trifluoromethyl)benzeneacetonitrile; 2-Methoxy-5-trifluoromethylphenylacetonitrile; 5-(Trifluoromethyl)-2-methoxyphenylacetonitrile; α-Cyano-2-methoxy-5-(trifluoromethyl)toluene; Benzeneacetonitrile, 2-methoxy-α-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.