Description

3-Fluoro-2-(Trifluoromethyl)Phenylacetonitrile, 97% is a high-purity fluorinated aromatic nitrile building block of significant synthetic utility. This compound is valued for its role in introducing both fluorine and the versatile nitrile functional group into complex molecular architectures, enabling the development of novel materials and active ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for use in medicinal chemistry, pesticide synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with enhanced activity and environmental profiles.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials requiring specific dielectric and optical properties.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart chemical resistance, thermal stability, and unique surface characteristics.
• Cross-Coupling Reactions: The nitrile and aryl halide moieties make it suitable for palladium-catalyzed coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new fluorination methodologies and constructing diverse chemical libraries.

Basic Information

Product Name	3-Fluoro-2-(Trifluoromethyl)Phenylacetonitrile, 97%
CAS No.	1000526-58-8
Molecular Formula	C9H5F4N
Molecular Weight	203.14 g/mol
Synonyms	2-(3-Fluoro-2-(trifluoromethyl)phenyl)acetonitrile; (3-Fluoro-2-(trifluoromethyl)phenyl)acetonitrile; α-Cyano-3-fluoro-2-(trifluoromethyl)toluene; 3-Fluoro-α-(trifluoromethyl)benzeneacetonitrile; 2-(Trifluoromethyl)-3-fluorobenzyl cyanide; 3-Fluoro-2-trifluoromethylphenylacetonitrile; 1000526-58-8
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-(Trifluoromethyl)Phenylacetonitrile is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. Our quality commitment supports your R&D and scale-up processes with reliable, consistent material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.