Description

2-Methyl-3-(Trifluoromethyl)Phenylacetonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the reactive nitrile functionality, enabling precise molecular construction. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in areas targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoromethylphenyl moiety into complex molecular architectures in medicinal and synthetic chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	2-Methyl-3-(Trifluoromethyl)Phenylacetonitrile
CAS No.	1000515-00-3
Molecular Formula	C10H8F3N
Molecular Weight	199.17 g/mol
Synonyms	2-Methyl-3-(trifluoromethyl)benzyl cyanide; [2-Methyl-3-(trifluoromethyl)phenyl]acetonitrile; 3-(Trifluoromethyl)-o-tolylacetonitrile; α-(2-Methyl-3-(trifluoromethyl)phenyl)acetonitrile; 2-(2-Methyl-3-(trifluoromethyl)phenyl)acetonitrile; (2-Methyl-3-trifluoromethylphenyl)acetonitrile; 2-Methyl-α-(trifluoromethyl)benzeneacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(Trifluoromethyl)Phenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. The container must be kept tightly closed and stored in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.