Description

2-Fluoro-5-Nitrophenylacetonitrile is a versatile and high-purity fluorinated nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitro group and a reactive nitrile, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated aromatic systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for creating fluorinated components in advanced electronic display and lighting materials.
• Cross-Coupling Reactions: The nitrile and halogen substituents make it a suitable substrate for palladium-catalyzed reactions like Suzuki and Sonogashira couplings.
• Heterocyclic Chemistry: Employed in the construction of various nitrogen-containing heterocycles, such as indoles, quinolines, and benzimidazoles, important in medicinal chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes and tags for studying biological processes.

Basic Information

Product Name	2-Fluoro-5-Nitrophenylacetonitrile
CAS No.	1000339-92-3
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	(2-Fluoro-5-nitrophenyl)acetonitrile; 2-Fluoro-5-nitrobenzyl cyanide; 2-Fluoro-5-nitrobenzeneacetonitrile; 2-Fluoro-5-nitro-α-tolunitrile; 2-Fluoro-5-nitrobenzyl nitrile; 5-Nitro-2-fluorobenzyl cyanide; α-Cyano-2-fluoro-5-nitrotoluene; 2-Fluoro-5-nitrobenzeneacetonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitrophenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.