Description

2-Bromo-3-Fluorophenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of bromine and fluorine atoms is essential for modulating biological activity and physicochemical properties. It is primarily sought after by research chemists and process development scientists engaged in the creation of new active pharmaceutical ingredients (APIs), advanced agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the halogenated phenyl moiety enhances efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers and liquid crystals with specific electronic properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and imaging applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-3-Fluorophenylacetonitrile
CAS No.	1000339-53-6
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	(2-Bromo-3-fluorophenyl)acetonitrile; 2-Bromo-3-fluorobenzyl cyanide; α-Cyano-2-bromo-3-fluorotoluene; 2-Bromo-3-fluoro-α-tolunitrile; 2-Bromo-3-fluorobenzeneacetonitrile; (2-Bromo-3-fluorophenyl)methanenitrile; 1000339-53-6; Benzeneacetonitrile, 2-bromo-3-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Fluorophenylacetonitrile is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.