Description

Benzonitrile, 3-Fluoro-2-Nitro- is a high-purity fluorinated aromatic nitrile building block, identified by CAS NO 1000339-52-5. This compound is valued for its unique molecular structure, which combines a nitrile group with fluorine and nitro substituents, enabling precise chemical modifications in advanced synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of fluorinated tags and probes for studying biological mechanisms and diagnostics.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.
• Nitrile Transformation Chemistry: Used in reactions to convert the nitrile group into amides, acids, or heterocycles like tetrazoles.

Basic Information

Product Name	Benzonitrile, 3-Fluoro-2-Nitro-
CAS No.	1000339-52-5
Molecular Formula	C7H3FN2O2
Molecular Weight	166.11 g/mol
Synonyms	3-Fluoro-2-nitrobenzonitrile; 2-Nitro-3-fluorobenzonitrile; 3-Fluoro-2-nitro-benzonitrile; Benzonitrile, 3-fluoro-2-nitro-; 3-Fluoro-2-nitrobenzenecarbonitrile; 2-Cyano-6-fluoronitrobenzene; 2-Fluoro-6-nitrobenzonitrile (isomer check required); 3-Fluoro-2-nitro-phenyl cyanide
EINECS	Contact for details

Quality Control

Our Benzonitrile, 3-Fluoro-2-Nitro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.