Description

2-([(Benzyloxy)Carbonyl](2,2,2-Trifluoroethyl)Amino)Acetic Acid (Wxfc0780) is a specialized N-protected amino acid derivative, serving as a crucial building block in advanced organic synthesis. Its value lies in the combination of a benzyloxycarbonyl (Cbz) protecting group and a trifluoroethyl moiety, which imparts unique reactivity and stability for demanding chemical transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for constructing complex peptide mimetics and fluorinated compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in peptide and peptidomimetic drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides that incorporate fluorinated motifs for enhanced efficacy and environmental profile.
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis, where the Cbz group offers orthogonal protection strategies.
• Fluorine Chemistry Research: A valuable reagent for introducing the trifluoroethylaminoacetic acid scaffold into target molecules to study the effects of fluorine on bioavailability and metabolic stability.
• Chemical Biology Probes: Utilized in the design and synthesis of enzyme inhibitors, receptor ligands, and other molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-([(Benzyloxy)Carbonyl](2,2,2-Trifluoroethyl)Amino)Acetic Acid (Wxfc0780)
CAS No.	199340-78-8
Molecular Formula	C₁₂H₁₂F₃NO₄
Molecular Weight	291.22 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-N-(2,2,2-trifluoroethyl)glycine; 2-[[(Benzyloxy)carbonyl](2,2,2-trifluoroethyl)amino]acetic acid; (Benzyloxy)carbonyl(2,2,2-trifluoroethyl)aminoacetic Acid; Z-NH-CH₂-COOH (CF₃CH₂); Cbz-N(CF₃CH₂)-Gly-OH; N-Cbz-N-(2,2,2-trifluoroethyl)glycine; N-(Benzyloxycarbonyl)-N-(trifluoroethyl)glycine; WXFC0780
EINECS	Contact for details

Quality Control

Our 2-([(Benzyloxy)Carbonyl](2,2,2-Trifluoroethyl)Amino)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.