Description

Etiprednol Dicloacetate is a synthetic corticosteroid derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its potent anti-inflammatory and immunomodulatory properties, making it a key intermediate in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and R&D organizations focused on developing next-generation treatments for ophthalmic, dermatological, and systemic inflammatory conditions.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel corticosteroid-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Development: Used in research for formulating advanced anti-inflammatory eye drops and treatments for conditions like uveitis and allergic conjunctivitis.
• Dermatological Preparations: Investigated for use in topical creams and ointments targeting psoriasis, eczema, and other inflammatory skin disorders.
• Anti-inflammatory Research: Acts as a reference standard and experimental compound in preclinical studies exploring new mechanisms for modulating immune response.
• Veterinary Medicine: Potential application in developing anti-inflammatory treatments for companion and livestock animals.
• Analytical Standard: Employed as a high-purity reference material in quality control (QC) and analytical method development within regulatory and laboratory settings.

Basic Information

Item	Details
Product Name	Etiprednol Dicloacetate
CAS No.	199331-40-3
Molecular Formula	C26H32Cl2O7
Molecular Weight	527.44 g/mol
Synonyms	Etiprednol Dicloacetate; 11β,17α,21-Trihydroxy-16α-ethylpregna-1,4-diene-3,20-dione 21-(2,2-dichloroacetate); 21-(Dichloroacetoxy)-11β,17α-dihydroxy-16α-ethylpregna-1,4-diene-3,20-dione; 16α-Ethyl-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione 21-(2,2-dichloroacetate); Etiprednol Dichloroacetate; ZK 91588
EINECS	Contact for details

Quality Control

Our Etiprednol Dicloacetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practice (cGMP) guidelines where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by advanced analytical techniques including HPLC, NMR, and MS. We support compliance with major pharmacopoeial standards (USP/EP) and regulatory frameworks (FDA, ICH Q7).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.