Description

2-Fluoro-6-Methylbenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require fluorinated aromatic motifs for enhanced activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for incorporating fluorine atoms into molecular probes for studying biological systems and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and fine chemical companies for bespoke synthesis projects requiring fluorinated benzonitrile derivatives.

Basic Information

Product Name	2-Fluoro-6-Methylbenzonitrile
CAS No.	198633-76-0
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	2-Fluoro-6-methylbenzonitrile; 6-Methyl-2-fluorobenzonitrile; 2-Fluoro-6-tolunitrile; o-Fluoro-m-tolunitrile; 2-Fluoro-6-methylphenyl cyanide; Benzonitrile, 2-fluoro-6-methyl-; (2-Fluoro-6-methylphenyl)carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided for every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.