Description

Pipendoxifene CAS NO 198480-55-6 is a selective estrogen receptor modulator (SERM) known for its high binding affinity and specificity. This compound is a critical intermediate and research chemical for developing novel therapeutic agents targeting hormone-dependent conditions. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in oncology and endocrinology research.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of advanced SERM candidates for preclinical and clinical studies.
• Biochemical Assay Development: Used as a reference standard or ligand in competitive binding assays to study estrogen receptor (ER) activity and screen for new modulators.
• Academic Research: Employed in university and institutional labs to investigate the mechanisms of estrogen signaling, breast cancer progression, and bone metabolism.
• Drug Discovery Programs: A vital building block for medicinal chemists working on next-generation therapies for hormone-receptor-positive (HR+) cancers and other endocrine disorders.
• Fine Chemical Synthesis: Used in custom synthesis and contract manufacturing for producing high-value, specialized chemical entities.

Basic Information

Product Name	Pipendoxifene
CAS No.	198480-55-6
Molecular Formula	C26H28N2O3
Molecular Weight	416.52 g/mol
Synonyms	Pipendoxifene; ERA-923; (7R)-7-(4-{2-[(1R)-1-(4-Hydroxyphenyl)-1-methylethyl]-1H-pyrrol-1-yl}butoxy)-3,4-dihydro-2H-1-benzopyran-4-ol; 4-[2-(1-Pyrrolidinyl)ethoxy]biphenyl-4'-carboxamide; ERA 923; ERA-923; TAS-108 (related development code)
EINECS	Contact for details

Quality Control

Our Pipendoxifene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports GLP (Good Laboratory Practice) standards for reliable and reproducible research outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.