Description

Benzonitrile, 2-Fluoro-3-Methoxy- (9Ci) CAS NO 198203-94-0 is a high-purity fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its unique molecular structure, featuring both fluorine and methoxy substituents, makes it a critical intermediate for introducing specific electronic and steric properties into target molecules. This compound is primarily sought by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including kinase inhibitors and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce polar nitrile and fluorinated groups into specialty polymers for enhanced chemical resistance.
• Chemical Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create diverse biaryl and heterocyclic structures.
• Material Science Research: Investigated for use in the creation of novel metal-organic frameworks (MOFs) and porous materials with tailored properties.

Basic Information

Product Name	Benzonitrile, 2-Fluoro-3-Methoxy- (9Ci)
CAS No.	198203-94-0
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	2-Fluoro-3-methoxybenzonitrile; 3-Methoxy-2-fluorobenzonitrile; 2-Fluoro-3-methoxybenzenecarbonitrile; 2-Fluoro-m-anisonitrile; 2-Fluoro-3-methoxyphenyl cyanide; Benzonitrile, 2-fluoro-3-methoxy-; 2-Fluoro-3-methoxy phenyl cyanide
EINECS	Contact for details

Quality Control

Our Benzonitrile, 2-Fluoro-3-Methoxy- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with ISO standards and the stringent requirements of cGMP for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider maintaining under an inert atmosphere to preserve optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0% (Area %)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.