Description

1,3-Difluoro-2,4-dimethoxy-5-nitrobenzene is a high-purity, multi-functional aromatic intermediate of significant importance in advanced organic synthesis. Its unique substitution pattern, featuring fluorine, methoxy, and nitro groups, makes it a versatile building block for constructing complex molecular architectures. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated, electron-deficient aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex nitro- and methoxy-substituted dyes and organic pigments.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of reactive fluorine atoms.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial laboratories.

Basic Information

Product Name	1,3-Difluoro-2,4-dimethoxy-5-nitrobenzene
CAS No.	195136-63-1
Molecular Formula	C8H7F2NO4
Molecular Weight	219.14 g/mol
Synonyms	2,4-Dimethoxy-1,3-difluoro-5-nitrobenzene; 5-Nitro-1,3-difluoro-2,4-dimethoxybenzene; Benzene, 1,3-difluoro-2,4-dimethoxy-5-nitro-; 1,3-Difluoro-2,4-dimethoxy-5-nitro-benzene; 195136-63-1; DFDMNB
EINECS	Contact for details

Quality Control

Every batch of 1,3-Difluoro-2,4-dimethoxy-5-nitrobenzene is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.