Description

2,4-Dimethoxy-5-Fluoronitrobenzene is a high-purity fluorinated nitrobenzene derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring strategically placed methoxy and fluoro substituents adjacent to a nitro group, makes it an essential intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Agrochemical Synthesis: Building block for developing advanced herbicides, pesticides, and fungicides that benefit from the stability and bioactivity of the fluoronitrobenzene core.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group and aromatic stability.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing complex, color-fast dyes and organic pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures common in many advanced compounds.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and methodologies in academic and industrial R&D laboratories.

Basic Information

Product Name	2,4-Dimethoxy-5-Fluoronitrobenzene
CAS No.	195136-62-0
Molecular Formula	C8H8FNO4
Molecular Weight	201.15 g/mol
Synonyms	1-Fluoro-2,4-dimethoxy-5-nitrobenzene; 5-Fluoro-2,4-dimethoxynitrobenzene; Benzene, 1-fluoro-2,4-dimethoxy-5-nitro-; 2,4-Dimethoxy-5-fluoronitrobenzene; 5-Fluoro-1,3-dimethoxy-2-nitrobenzene; 2-Nitro-5-fluoro-1,3-dimethoxybenzene
EINECS	Contact for details

Quality Control

Our 2,4-Dimethoxy-5-Fluoronitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.