Description

3,3'-Dinitro-5,5'-Bis(trifluoromethyl)biphenyl is a high-value, multi-functional biphenyl derivative engineered for advanced chemical synthesis. This compound is a critical building block in the development of specialty materials and active pharmaceutical ingredients (APIs), offering unique reactivity due to its electron-deficient aromatic system and trifluoromethyl groups. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorinated and nitro-substituted motifs into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides where the nitro and trifluoromethyl groups contribute to biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in catalysis, especially in cross-coupling and other transition metal-catalyzed reactions.
• Advanced Material Research: Employed in the synthesis of monomers for high-performance polymers, liquid crystals, and electronic materials where fluorination improves thermal and chemical resistance.
• Organic Synthesis Building Block: Provides a versatile scaffold for further functionalization, including reduction of nitro groups to amines, facilitating the construction of complex heterocycles and dyes.

Basic Information

Product Name	3,3'-Dinitro-5,5'-Bis(trifluoromethyl)biphenyl
CAS No.	194344-28-0
Molecular Formula	C14H6F6N2O4
Molecular Weight	380.21 g/mol
Synonyms	5,5'-Bis(trifluoromethyl)-3,3'-dinitrobiphenyl; 3,3'-Dinitro-5,5'-bis(trifluoromethyl)-1,1'-biphenyl; [1,1'-Biphenyl]-3,3'-dinitro-5,5'-bis(trifluoromethyl)-; 3,3'-Dinitro-5,5'-di(trifluoromethyl)biphenyl; 5,5'-(Trifluoromethyl)-3,3'-dinitrobiphenyl
EINECS	Contact for details

Quality Control

Our 3,3'-Dinitro-5,5'-Bis(trifluoromethyl)biphenyl is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.