Description

3-(4-Fluoro-Benzyl)-Pyrrolidine is a high-purity fluorinated pyrrolidine derivative, a crucial nitrogen-containing heterocyclic building block in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a pyrrolidine ring with a fluorinated benzyl group, enabling precise structural modifications for advanced material and pharmaceutical development. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated motifs for enhanced bioactivity, metabolic stability, or material properties.

Application

This versatile fluorinated intermediate is designed for high-value synthesis across multiple advanced industries.

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides where the fluorine atom improves efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science Research: Incorporated into the design of advanced polymers, liquid crystals, or organic electronic materials to tune electronic properties and stability.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(4-Fluoro-Benzyl)-Pyrrolidine
CAS No.	193220-17-6
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	3-[(4-Fluorophenyl)methyl]pyrrolidine; 1-(4-Fluorobenzyl)pyrrolidin-3-amine (tautomer consideration); 4-Fluoro-α-(3-pyrrolidinyl)methylbenzene; Pyrrolidine, 3-[(4-fluorophenyl)methyl]-; 193220-17-6; 3-(4-Fluorobenzyl)pyrrolidine; 3-(p-Fluorobenzyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoro-Benzyl)-Pyrrolidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity building blocks for research and cGMP (current Good Manufacturing Practice) development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.