Description

3,3,3-Trifluoroalanine Ethyl Ester Hydrochloride is a high-value fluorinated amino acid derivative, essential for introducing the metabolically stable trifluoromethyl group into complex molecules. This compound serves as a critical chiral building block in pharmaceutical research and development, enabling the synthesis of novel bioactive compounds with enhanced properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating fluorinated analogs and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptidomimetics & Protease Inhibitors: Used in the design and construction of fluorinated peptide analogs to modulate stability, bioavailability, and binding affinity.
• Agrochemical Research: Employed in the development of novel fluorinated herbicides, pesticides, and plant growth regulators.
• Fluorine Chemistry & Methodology Development: Serves as a standard substrate or reagent in studies exploring new fluorination reactions or asymmetric synthesis techniques.
• Material Science Precursor: Potential use in creating fluorinated organic frameworks or specialty polymers with unique surface properties.
• Bioconjugation & Probe Synthesis: Useful for labeling biomolecules or synthesizing imaging agents and diagnostic probes containing fluorine tags.

Basic Information

Product Name	3,3,3-Trifluoroalanine Ethyl Ester Hydrochloride
CAS No.	193140-71-5
Molecular Formula	C5H9F3NO2·HCl
Molecular Weight	223.59 g/mol (Free base: 187.12 g/mol)
Synonyms	L-3,3,3-Trifluoroalanine ethyl ester hydrochloride; Ethyl (2S)-2-amino-4,4,4-trifluorobutanoate hydrochloride; (S)-Ethyl 2-amino-4,4,4-trifluorobutanoate hydrochloride; 4,4,4-Trifluoro-L-alanine ethyl ester hydrochloride; 3,3,3-Trifluoro-L-alanine ethyl ester HCl; Ethyl 3,3,3-trifluoroalaninate hydrochloride; Alanine, 3,3,3-trifluoro-, ethyl ester, hydrochloride, L-
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoroalanine Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.