Description

2-Fluoro-4-Nitro-1-(Trifluoromethoxy)Benzene is a high-value, multi-functional aromatic building block distinguished by its unique combination of fluorine, nitro, and trifluoromethoxy substituents. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its structure imparts critical properties like metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, including kinase inhibitors and anti-inflammatory agents.
• Agrochemical Research: Used to develop new generations of herbicides and pesticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting materials.
• Functional Material Synthesis: Building block for advanced polymers, ligands, and catalysts requiring specific electronic properties.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated colorants.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions.

Basic Information

Product Name	2-Fluoro-4-Nitro-1-(Trifluoromethoxy)Benzene
CAS No.	190902-95-5
Molecular Formula	C7H3F4NO3
Molecular Weight	225.10 g/mol
Synonyms	1-Fluoro-2-Nitro-4-(Trifluoromethoxy)Benzene; 2-Fluoro-4-Nitro-1-(Trifluoromethoxy)Benzene; 2-Fluoro-4-Nitrophenyl Trifluoromethyl Ether; 4-Nitro-2-Fluorophenyl Trifluoromethyl Ether; 2-Fluoro-4-Nitro-alpha,alpha,α-Trifluoroanisole; Benzene, 2-fluoro-4-nitro-1-(trifluoromethoxy)-; 190902-95-5
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Nitro-1-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.