Description

Bepotastine CAS NO 190786-43-7 is a potent, selective histamine H1 receptor antagonist widely recognized for its anti-allergic properties. This active pharmaceutical ingredient (API) is critical for developing effective treatments that manage allergic responses with a favorable safety profile. It is primarily required by pharmaceutical manufacturers and R&D organizations focused on ophthalmic solutions, nasal sprays, and oral formulations for allergic conjunctivitis, rhinitis, and related conditions.

Application

• Active Pharmaceutical Ingredient (API) in ophthalmic anti-allergy solutions for treating allergic conjunctivitis.
• Key component in nasal spray formulations targeting allergic rhinitis and hay fever symptoms.
• Raw material for the development and production of oral anti-allergic medications.
• Reference standard in pharmaceutical quality control and analytical method development.
• Critical intermediate in advanced pharmacological research studying histamine receptor mechanisms.
• Used in formulation development for novel drug delivery systems.

Basic Information

Product Name	Bepotastine
CAS No.	190786-43-7
Molecular Formula	C21H25ClN2O3
Molecular Weight	388.89 g/mol
Synonyms	Bepotastine Besilate; Bepotastine Besylate; TAU-284; (+)-4-[(S)-p-Chloro-α-(2-pyridyl)benzyloxy]-1-methylpiperidine; (S)-4-[p-Chloro-α-(2-pyridyl)benzyloxy]-1-methylpiperidine; 4-[(S)-(4-Chlorophenyl)(2-pyridinyl)methoxy]-1-methylpiperidine; Bepreve (brand name ophthalmic solution); Taliou (brand name)
EINECS	Contact for details

Quality Control

Our Bepotastine is manufactured under strict quality management systems to meet the rigorous standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via HPLC, to ensure compliance with ICH guidelines. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for pharmaceutical-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.