Description

Benzonitrile, 2-Amino-3,6-Difluoro- (9Ci) is a high-purity, multi-functional aromatic nitrile building block distinguished by its amino and difluoro substitution pattern. This compound is critical for advanced organic synthesis, enabling the precise introduction of a functionalized aromatic core into complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-cancer agent research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the fluorine atoms for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Functional Material Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers.
• Fluorinated Building Block: Provides a versatile scaffold for further derivatization in medicinal and combinatorial chemistry.
• Research & Development: Essential for academic and industrial R&D exploring new chemical entities and structure-activity relationships.

Basic Information

Product Name	Benzonitrile, 2-Amino-3,6-Difluoro- (9Ci)
CAS No.	190011-81-5
Molecular Formula	C7H4F2N2
Molecular Weight	154.12 g/mol
Synonyms	2-Amino-3,6-difluorobenzonitrile; 3,6-Difluoro-2-aminobenzonitrile; 2-Cyano-3,6-difluoroaniline; 2-Amino-3,6-difluorophenyl cyanide; 190011-81-5; Benzonitrile, 2-amino-3,6-difluoro-; 2-Amino-3,6-difluoro-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3,6-difluorobenzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.