Description

2-Fluoro-4-Nitro-1-Phenoxy-Benzene is a high-purity fluorinated aromatic nitro compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This product is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries seeking reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, pesticides, and fungicides, where the nitro and fluoro groups impart specific biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing complex dyes and pigments, leveraging its nitro-aromatic core.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures.
• Academic & Industrial R&D: Employed in exploratory chemistry for developing new synthetic methodologies and discovering novel compounds.

Basic Information

Product Name	2-Fluoro-4-Nitro-1-Phenoxy-Benzene
CAS No.	189181-21-3
Molecular Formula	C12H8FNO3
Molecular Weight	233.20 g/mol
Synonyms	1-Fluoro-2-Nitro-4-Phenoxybenzene; 4-Nitro-2-Fluorodiphenyl Ether; 2-Fluoro-4-Nitrodiphenyl Ether; 1-Phenoxy-2-Fluoro-4-Nitrobenzene; (2-Fluoro-4-nitrophenyl) Phenyl Ether; 2-Fluoro-4-nitrophenyl Phenyl Ether; NSC 405124; 4-Nitro-2-fluorophenyl Phenyl Ether
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Nitro-1-Phenoxy-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.