Description

2-Amino-5-Chloro-3-Fluoro-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique halogenated aniline structure, which makes it a critical intermediate in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antimicrobials, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct advanced fungicides, herbicides, and insecticides, leveraging its halogen and amino groups for bioactivity.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and creating custom chemical libraries.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex, halogenated dyes and functional pigments.

Basic Information

Product Name	2-Amino-5-Chloro-3-Fluoro-Benzonitrile
CAS No.	187805-49-8
Molecular Formula	C7H4ClFN2
Molecular Weight	170.57 g/mol
Synonyms	5-Chloro-3-fluoro-2-aminobenzonitrile; 2-Amino-5-chloro-3-fluorobenzonitrile; 3-Fluoro-2-amino-5-chlorobenzonitrile; Benzonitrile, 2-amino-5-chloro-3-fluoro-; 2-Amino-3-fluoro-5-chlorobenzonitrile; 187805-49-8; 5-Chloro-3-fluoroanthranilonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Chloro-3-Fluoro-Benzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.