Description

4-Fluoro-3-Hydroxybenzonitrile 98 is a high-purity fluorinated aromatic nitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a cyano and a hydroxyl group on a fluorinated benzene ring, makes it an invaluable intermediate for creating complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to introduce polar cyano and hydroxyl functionalities into specialty polymers.
• Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to construct biaryl systems.
• Dye & Pigment Manufacturing: Intermediate for synthesizing fluorinated chromophores with enhanced light-fastness and color properties.

Basic Information

Product Name	4-Fluoro-3-Hydroxybenzonitrile 98
CAS No.	186590-04-5
Molecular Formula	C7H4FNO
Molecular Weight	137.11 g/mol
Synonyms	3-Hydroxy-4-fluorobenzonitrile; 4-Fluoro-3-hydroxybenzonitrile; 2-Fluoro-5-cyanophenol; 5-Cyano-2-fluorophenol; 2-Fluor-5-cyanphenol (German); 4-Fluoro-3-hydroxybenzenecarbonitrile; Phenol, 2-fluoro-5-cyano-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Hydroxybenzonitrile 98 is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure it meets the specified 98% minimum purity and impurity profile. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformance to specifications. Our quality commitment supports applications requiring high consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.