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2,3-Dichloro-6-(Trifluoromethyl)Benzonitrile CAS NO 186517-39-5


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CAS No.:186517-39-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,3-Dichloro-6-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional aromatic intermediate featuring a benzonitrile core with chloro and trifluoromethyl substituents. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where its unique halogenated and fluorinated structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

  • Agrochemical Intermediate: A key synthon for the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and dichloro motifs.
  • Pharmaceutical Building Block: Used in medicinal chemistry research for the synthesis of drug candidates, particularly in areas requiring lipophilicity and electronic modulation.
  • Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic semiconductors.
  • Polymer Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
  • Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactivity of its chloro substituents.
  • Chemical Research & Development: Employed as a standard or reference compound in analytical method development and pathway exploration.

Basic Information

Product Name 2,3-Dichloro-6-(Trifluoromethyl)Benzonitrile
CAS No. 186517-39-5
Molecular Formula C8H2Cl2F3N
Molecular Weight 240.01 g/mol
Synonyms 2,3-Dichloro-α,α,α-trifluoro-p-tolunitrile; 6-(Trifluoromethyl)-2,3-dichlorobenzonitrile; 2,3-Dichloro-6-trifluoromethylbenzonitrile; 2,3-Dichloro-α,α,α-trifluoro-4-cyanotoluene; Benzeneacetonitrile, 2,3-dichloro-α,α,α-trifluoro-; 2,3-Dichloro-6-(trifluoromethyl)benzonitrile; 4-Cyano-2,3-dichlorobenzotrifluoride
EINECS Contact for details

Quality Control

Our 2,3-Dichloro-6-(Trifluoromethyl)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment ensures the material meets the high standards required for sensitive applications in synthesis and R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Unknown Impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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