Description

4-Fluoro-2-(2,2,2-trifluoroethoxy)nitrobenzene is a high-purity fluorinated aromatic nitro compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity imparted by the combination of fluorine, trifluoroethoxy, and nitro functional groups, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in creating novel herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for fluorinated liquid crystals, polymers, and specialty materials.
• Organic Synthesis: A versatile reagent for introducing fluorinated alkoxy and nitroaryl motifs into complex molecules via cross-coupling and substitution reactions.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-Fluoro-2-(2,2,2-Trifluoroethoxy)Nitrobenzene
CAS No.	186386-91-4
Molecular Formula	C8H5F4NO3
Molecular Weight	239.12 g/mol
Synonyms	1-Fluoro-4-nitro-2-(2,2,2-trifluoroethoxy)benzene; 2-(2,2,2-Trifluoroethoxy)-4-fluoronitrobenzene; 4-Fluoro-2-(2,2,2-trifluoroethoxy)-1-nitrobenzene; Benzene, 1-fluoro-4-nitro-2-(2,2,2-trifluoroethoxy)-; 4-Fluoro-2-trifluoroethoxynitrobenzene; 186386-91-4; 4-Fluoro-2-(2,2,2-trifluoroethoxy)nitrobenzene
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(2,2,2-trifluoroethoxy)nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.