Description

1-(3,4-Difluorophenyl)Cyclopropane-1-Carbonitrile is a high-value, multi-functional organic intermediate featuring a cyclopropane ring and a nitrile group on a difluorinated aromatic scaffold. This compound matters for its role as a critical building block in modern synthetic chemistry, enabling the development of complex molecules with tailored properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique structure imparts desirable metabolic stability and binding characteristics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluorophenyl moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, contributing to unique optical and electronic properties.
• Chemical Biology Probes: Utilized as a core structure for developing molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	1-(3,4-Difluorophenyl)Cyclopropane-1-Carbonitrile
CAS No.	186347-65-9
Molecular Formula	C10H7F2N
Molecular Weight	179.17 g/mol
Synonyms	1-(3,4-Difluorophenyl)cyclopropanecarbonitrile; 1-(3,4-Difluorophenyl)cyclopropanecarbonitrile; 3,4-Difluoro-α-(cyclopropylcarbonyl)benzonitrile; Cyclopropane-1-carbonitrile, 1-(3,4-difluorophenyl)-; 186347-65-9; 1-(3,4-Difluorophenyl)-1-cyclopropanecarbonitrile; 1-Cyclopropane-1-carbonitrile-3,4-difluorobenzene
EINECS	Contact for details

Quality Control

Our 1-(3,4-Difluorophenyl)Cyclopropane-1-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.