Description

4-Ethoxy-2-Fluorobenzonitrile is a high-purity fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its core value lies in its dual functional groups, which allow for versatile derivatization, making it a critical intermediate for creating complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom and nitrile group enhance biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays (LCDs).
• Organic Electronic Materials: Employed in the development of electron-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: Valuable substrate for further fluorination reactions and the study of fluorine effects on molecular properties.

Basic Information

Product Name	4-Ethoxy-2-Fluorobenzonitrile
CAS No.	186191-34-4
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	2-Fluoro-4-ethoxybenzonitrile; 4-Ethoxy-2-fluorobenzonitrile; Benzonitrile, 4-ethoxy-2-fluoro-; 2-Fluoro-4-ethoxybenzonitrile; 186191-34-4; 4-Ethoxy-2-fluorobenzene carbonitrile; p-Ethoxy-o-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Ethoxy-2-Fluorobenzonitrile is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.