Description

3-Fluoro-4-(Methylsulphonyl)Benzonitrile is a high-value, multi-functional aromatic intermediate featuring both a sulfone and a nitrile group. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the development of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis.
• Material Science Research: Investigated as a monomer or additive for high-performance polymers and liquid crystals.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke chemical synthesis projects in CROs and CDMOs.

Basic Information

Product Name	3-Fluoro-4-(Methylsulphonyl)Benzonitrile
CAS No.	185946-05-8
Molecular Formula	C8H6FNO2S
Molecular Weight	199.20 g/mol
Synonyms	4-Cyano-2-fluoro-1-(methylsulfonyl)benzene; 2-Fluoro-4-cyanophenyl methyl sulfone; 3-Fluoro-4-(methylsulfonyl)benzonitrile; 4-(Methylsulfonyl)-3-fluorobenzonitrile; Benzonitrile, 3-fluoro-4-(methylsulfonyl)-; 185946-05-8; 3-Fluoro-4-methanesulfonylbenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Methylsulphonyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.