Description

4-(Benzyloxy)-2-Fluorobenzonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a benzyl-protected phenolic ether and a strategically placed fluorine atom adjacent to the nitrile group, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. It serves as a key precursor for the development of novel active ingredients, where its unique substitution pattern enables precise modulation of biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Monomer: Employed in the development of specialty polymers and high-performance resins with tailored thermal and chemical resistance properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry, cross-coupling reactions, and heterocycle formation.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments that offer improved lightfastness and color properties.

Basic Information

Product Name	4-(Benzyloxy)-2-Fluorobenzonitrile
CAS No.	185836-35-5
Molecular Formula	C14H10FNO
Molecular Weight	227.24 g/mol
Synonyms	2-Fluoro-4-(phenylmethoxy)benzonitrile; Benzonitrile, 4-(benzyloxy)-2-fluoro-; 4-Benzyloxy-2-fluorobenzonitrile; 2-Fluoro-4-benzyloxybenzonitrile; 4-(Benzyloxy)-2-fluorophenyl cyanide; 185836-35-5; 4-(Phenylmethoxy)-2-fluorobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-(Benzyloxy)-2-Fluorobenzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Our standard quality control includes rigorous testing for identity, purity, and impurity profiles using techniques such as HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.